Effect of “Yojyo Henshiko, a new Chinese herb Prescription”on serum ALT(GPT) and AST(GOT) levels in patients with hepatic diseases
S. Sha (Institute of Health Care with Oriental Herb and Medicine, Tokyo, Japan) M.Harada(Harada Hospital, Saitama, Japan) N. Yanaihara (Yanaihara Institute Inc., Shizuoka, Japan)
1999/12/12-16/
[BACK GROUND]
"Yojyo Henshiko", a new Chinese herb prescription, is composed of panax
pseudo-ginseng, eucomiac ulmoides, garlic acid-containing herbal extracts and
licorice root. This prescription has been found to be effective in lowering
serum levels of ALT(GPT) and AST(GOT) in rats with hepatic disease induced by D-glucosamine.
In the present study, we examined the effect of the prescription on patients
with liver diseases including hepatitis C virus (HCV) infection.
[METHODS]
The prescription (1g) was given after each meal three times per day to
patients with hepatic diseases under the control of physicians in a hospital.
[RESULTS AND DISCUSSION]
Serum levels of ALT(GPT) and AST(GOT) in the seven patients treated, including four
patients suffered from HCV, were markedly lowered after treatment with the
prescription for 10 days. In the four patients with HCV, the mean reductions
in ALT(GPT) and AST(GOT) were 21% and 72%, respectively. These results substantiate clearly
the effect of Yojyo Henshiko in lowering enhanced serum ALT(GPT) and AST(GOT) in patients
with hepatic disease.
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